562 EFFICACY SAFETY AND TOLERABILITY OF DIACEREIN MR 100mg vs DIACEREIN 50mg IN ADULT PATIENTS WITH OSTEOARTHRITIS OF THE KNEE
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منابع مشابه
Clinical Efficacy and Safety of Diacerein in Osteoarthritis – A Review
First-line drug therapy in osteoarthritis (OA) is purely symptomatic, with analgesic agents such as acetaminophen and anti-inflammatory agents such as aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) being the most widely prescribed medications. However, these products need to be taken chronically, have serious side effects and may accelerate cartilage degradation. The ideal therapeut...
متن کاملEfficacy and safety of glucosamine, diacerein, and NSAIDs in osteoarthritis knee: a systematic review and network meta-analysis
BACKGROUND To conduct a systematic review and network meta-analysis of randomized controlled trials (RCTs) with the aims of comparing relevant clinical outcomes (that is, visual analog scores (VAS), total and sub-Western Ontario and McMaster Universities Osteoarthritis index (WOMAC) scores, Lequesne algofunctional index, joint space width change, and adverse events) between diacerein, glucosami...
متن کاملEfficacy and Tolerability of Glucosamine - Chondroitin Sulphate - Methyl Sulfonyl Methane (MSM) in Osteoarthritis of Knee in Indian Patients
Background & Objective. Osteoarthritis is progressive degenerative disease resulting in significant affection of joints. Nonsteroidal anti-inflammatory drugs (NSAIDS) are widely used in this condition but are associated with significant side effects; hence the aim of this study was to evaluate the efficacy and tolerability of nutritional supplements such as Glucosamine, Chondroitin sulphate and...
متن کاملThe Efficacy of Diacerein with and Without Diclofenac Sodium on Knee Pain Severity and Walking Time in Patients with Knee Osteoarthritis
Introduction: Diacerein (4,5-diacetyloxy-9,10-dioxo-anthracene-2-carboxylic acid) appeared promising in osteoarthritis (OA) treatment for its IL-1β inhibitory properties. However, it is a slow-acting disease-modifying drug, and its effect would appear after few weeks of its intake. Therefore, it was suggested to be prescribed in combination with NSAID during the early few weeks of its administr...
متن کاملthe washback effect of discretepoint vs. integrative tests on the retention of content in knowledge tests
در این پایان نامه تاثیر دو نوع تست جزیی نگر و کلی نگر بر به یادسپاری محتوا ارزیابی شده که نتایج نشان دهندهکارایی تستهای کلی نگر بیشتر از سایر آزمونها است
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2010
ISSN: 1063-4584
DOI: 10.1016/s1063-4584(10)60589-4